Detection Period: Can be detected in urine up to 3-5 days after use
Detection Level: 1,000 ng/mL (d-Methamphetamine as the calibrator*)
Brief Description of Drug: Methamphetamine is an addictive stimulant drug that has a high potential for abuse and dependency. It is related to amphetamine but has a stronger effect on the central nervous system.
Typically Prescribed For:
- Attention deficit disorder with hyperactivity (ADHD)
- Obesity
Effects:
- Increased wakefulness and physical activity
- Decreased appetite
Forms: White pill or powder; crystal meth looks like pieces of glass or shiny blue-white “rocks” of different sizes
Methods of Consumption: Swallowed, snorted, smoked, injected
An increasingly common drug, methamphetamine is known for its powerful stimulant effects. According to the 2005 National Survey on Drug Use and Health (NSDUH), an estimated 10.4 million people aged 12 or older (4.3 percent of the population) have tried methamphetamine at some point in their lives. Methamphetamine is longer-lasting and has stronger effects on the central nervous system than amphetamine (National Institute on Drug Abuse).
Methamphetamine has limited medical uses, but the chemicals used to manufacture it are often illegally diverted from legitimate sources. Precursor chemicals include pseudoephedrine (found in over-the-counter cold medicines), anhydrous ammonia (used as an agricultural fertilizer and industrial refrigerant), and red phosphorus (used in matches).
Methamphetamine comes in various forms and can be smoked, snorted, injected, or orally ingested. Smoking meth leads to very rapid brain intake, which increases the potential for addiction and severe health implications.
Street methamphetamine is referred to by many names, such as “speed,” “meth,” and “chalk.” Methamphetamine hydrochloride, clear chunky crystals resembling ice, is known as “ice,” “crank,” “crystal,” “tina,” and "glass."
Symptoms of Meth Use: Signs of meth use include a euphoric high, loss of appetite, dilated pupils, and increased physical activity, eye movement, nervousness, body temperature, sweating, and talking. Long-term use can lead to extreme weight loss, severe dental problems (“meth mouth”), anxiety, confusion, insomnia, mood disturbances, and violent behavior. Chronic abusers may also exhibit paranoia, hallucinations, and delusions.
*The Methamphetamine urine drug test uses d-Methamphetamine as the calibrator for the stated 1,000 ng/mL testing level. The following table lists the concentrations of compounds (ng/mL) that are detected as positive in this urine drug test:
*The Methamphetamine urine drug test uses d-Methamphetamine as the calibrator for the stated 1,000 ng/mL testing level. The following table lists the concentrations of compounds (ng/mL) that are detected as positive in this urine drug test:
Compound | Detection Level (ng/mL) |
d-Methamphetamine | 1,000 ng/mL |
p-Hydroxymethamphetamine | 30,000 ng/mL |
l-Methamphetamine | 8,000 ng/mL |
Mephentermine | 50,000 ng/mL |
3,4-Methylenedioxymethamphetamine (MDMA) | 2,000 ng/mL |
DIRECTIONS FOR USE
Allow the test card and/or test strip, urine specimen, and/or controls to reach room temperature (15-30 degrees Celsios) prior to testing.
DIRECTIONS FOR SINGLE TEST CARD
- Bring the pouch to room temperature before opening it. Remove the test card from the sealed pouch and use it as soon as possible.
- Remove the cap.
- With the arrow pointing toward the urine specimen, immerse the test card vertically in the urine specimen for at least 10 to 15 seconds. Immerse the strip to at least the level of the wavy lines, but not above the arrow on the test card. Replace the cap and place the test card on a non-absorbent flat surface.
- Start the timer and wait for the colored line(s) to appear.
- The result should be read at 5 minutes. Results may be stable up to 1 hour after test initiation.
INTERPRETATION OF RESULTS
NEGATIVE:* Two lines appear. One colored line should be in the control region (C), and another apparent colored line should be in the test region(T). This negative result indicates that the marijuana concentration is below the detectable level (50 ng/mL).
*NOTE: The shade of color in the test line region (T) will vary, but it should be considered negative whenever there is even a faint line.
POSITIVE: One colored line appears in the control region (C). No line appears in the test region (T). This positive result indicates that the marijuana concentration exceeds the detectable level (50 ng/mL).
INVALID: Control line fails to appear. Insufficient specimen volume or incorrect procedural techniques are the most likely reasons for control line failure. Review the procedure and repeat the test using a new test card or test strip. If the problem persists, discontinue use of the lot immediately and contact your distributor.
1. What is the significance of using d-Methamphetamine as the calibrator in drug testing?
Answer: Using d-Methamphetamine as the calibrator means that the test is specifically designed to detect methamphetamine at a cutoff level of 1,000 ng/mL. This ensures that the test is sensitive to the presence of methamphetamine and related compounds, providing accurate results for recent use.
2. Can prescription medications cause a positive drug test for methamphetamine?
Answer: Yes, certain prescription medications containing methamphetamine or amphetamine can cause a positive drug test. It is important to inform the testing administrator about any prescription medications you are taking and provide documentation from your healthcare provider. This will help differentiate between legitimate medical use and illicit use.
3. How effective are instant home drug tests for detecting methamphetamine?
Answer: Instant home drug tests for methamphetamine are highly convenient and provide quick results, often within minutes. They are designed to be user-friendly, making them accessible for anyone to administer. When used correctly, these tests offer accurate detection of methamphetamine use, helping to identify recent drug use efficiently. While laboratory-based tests are more comprehensive, home tests are a reliable first step in screening and can be followed up with lab confirmation if needed. The combination of convenience, speed, and accuracy makes instant home drug tests a valuable tool for families, small businesses, and schools looking to maintain a drug-free environment.
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